Estimated Reading Time: 11 minutes During the COVID-19 pandemic, there is an urgent need for the development of rapid and efficient detection systems. This article emphasizes the significance of biosensors in the context of COVID-19 control. It focuses on electrochemical methods for detecting COVID-19 and highlights biosensors’ unique advantages and limitations compared to other detection methods. The article also discusses recent advancements in biosensor technology, their integration with digital health technologies, and potential future applications. It delves into the challenges associated with biosensors, including technical and operational obstacles, as well as risk management strategies. This comprehensive review aims to serve as a critical reference for researchers and healthcare professionals in effectively managing the pandemic.